钱付平
发布时间:2021-09-03   浏览次数:10


钱付平 博士,讲师

   

2021年毕业于东南大学,获理学博士学位。同年,入职南通大学生命科学学院。主要通过单细胞RNA测序技术、CRISPR/Cas9基因编辑技术等研究相关基因在感觉毛细胞发育和再生中的作用机制。目前,已在AgingPLoS GeneticsFrontiers in Molecular NeuroscienceBiomaterials等期刊上发表研究论文9篇。


研究方向:

(1)感觉毛细胞(sensory hair cell)发育和功能调控的分子机制。

(2)毛细胞再生(hair cell regeneration)的基因调控机制。

 

发表论文:

(1)       Qian, F., Wang, X., Yin, Z., Xie, G., Yuan, H., Liu, D., and Chai, R. (2020). The slc4a2b gene is required for hair cell development in zebrafish. Aging (Albany NY) 12, 18804-18821.

(2)       Zhang, L.*, Gao, Y.*, Zhang, R.*, Sun, F., Cheng, C., Qian, F., Duan, X., Wei, G., Sun, C., Pang, X., et al. (2020). THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis. PLoS Genet 16, e1008953.

(3)       He, Y.*, Lu, X.*, Qian, F.*, Liu, D., Chai, R., and Li, H. (2017). Insm1a Is Required for Zebrafish Posterior Lateral Line Development. Front Mol Neurosci 10, 241.

(4)       Gong, J.*, Wang, X.*, Zhu, C., Dong, X., Zhang, Q., Wang, X., Duan, X., Qian, F., Shi, Y., Gao, Y., et al. (2017). Insm1a Regulates Motor Neuron Development in Zebrafish. Front Mol Neurosci 10, 274.

(5)       Yu, X., Liu, W., Fan, Z., Qian, F., Zhang, D., Han, Y., Xu, L., Sun, G., Qi, J., Zhang, S., et al. (2017). c-Myb knockdown increases the neomycin-induced damage to hair-cell-like HEI-OC1 cells in vitro. Sci Rep 7, 41094.

(6)       Guo, R.*, Zhang, S.*, Xiao, M.*, Qian, F., He, Z., Li, D., Zhang, X., Li, H., Yang, X., Wang, M., et al. (2016). Accelerating bioelectric functional development of neural stem cells by graphene coupling: Implications for neural interfacing with conductive materials. Biomaterials 106, 193-204.

(7)       He, Z.*, Sun, S.*, Waqas, M., Zhang, X., Qian, F., Cheng, C., Zhang, M., Zhang, S., Wang, Y., Tang, M., et al. (2016). Reduced TRMU expression increases the sensitivity of hair-cell-like HEI-OC-1 cells to neomycin damage in vitro. Sci Rep 6, 29621.

(8)       Guan, M., Fang, Q., He, Z., Li, Y., Qian, F., Qian, X., Lu, L., Zhang, X., Liu, D., Qi, J., et al. (2016). Inhibition of ARC decreases the survival of HEI-OC-1 cells after neomycin damage in vitro. Oncotarget 7, 66647-66659.

(9)       Li, B.*, Yang, X.Y.*, Qian, F.P., Tang, M., Ma, C., and Chiang, L.Y. (2015). A novel analgesic approach to optogenetically and specifically inhibit pain transmission using TRPV1 promoter. Brain Res 1609, 12-20.