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巩杰

日期:2020-01-01   点击数:45  


姓名:巩杰

出生年月:1987.01

职称:副教授、硕士生导师

部门:生命科学学院

联系方式:Tel: 18806287840

Fax: 86-(513)85012810 (O)

Email: jgong188@ntu.edu.cn

学历及学术经历:

2015/8至今     南通大学

2018/9-2019/09,美国加州大学旧金山分校     访问学者

2014/12-2015/03,詹姆斯库克大学,          交流访学博士生

2010/09-2015/06,厦门大学,海洋生物学,     博士,导师:李少菁教授、叶海辉教授。

  2006/09-2010/06,泰山学院,生物科学,      学士。

研究领域斑马鱼神经发育以及神经退行性疾病研究

研究课题:

1. 国家自然科学基金青年基金,项目名称:雌激素相关受体及其信号通路在三疣梭子蟹卵巢发育过程中的功能探究,项目起止年月:201701月至 201912月,19.00万元,主持。

2. 江苏省自然科学基金青年基金,项目名称:Insm-1b调控斑马鱼运动神经元发育以及成年自发性脊髓再生过程的机制,项目起止年月:20167月至20196月,20.00万元,主持。

3. 国家自然科学基金面上项目,项目名称:遗传性耳聋新致病基因THOC1的听觉功能及致聋机制研究,项目起止年月: 201901月至 202212月,57万,参与。

4. 国家自然科学基金青年基金,项目批准号:81801281,项目名称:GABRG2突变在癫痫性脑病发生中的机制研究,项目起止年月:201901月至 202112月,21万,参与。

5. 国家自然科学基金面上项目,项目批准号:81870359,项目名称:Aquaporins调控血管新生过程中管腔形成的机制研究,项目起止年月:201901月至 202212月,60万,参与。

代表性论文

  1. Gong J, Hu SQ, Huang ZG, Hu YB, Wang XN, Zhao JX, Qian PP, Sheng JJ, Lu XF, Wei GY*, Liu D*. 2020. The requirement of Sox2 for the spinal cord motor neuron development of zebrafish. Frontiers in Molecular Neuroscience, doi: 10.3389/fnmol.2020.00034

  2.  Gong J, Shi W, Zhang M, Wang T, Yu K, Ye, H*. 2019. Characterization and expression analysis of E75 during ovarian development and juvenile growth of the mud crab, Scylla paramamosain Estampador, 1950 (Brachyura, Portunidae). Crustaceana, 92(9), 1063-1079.

  3.  Liu, MM#, Pan, J, Dong, ZG, Cheng, YX, Gong, J*, Wu, XG*. 2019. Comparative transcriptome reveals the potential modulation mechanisms of estradiol affecting ovarian development of female Portunus trituberculatus. Plos One, 14(12): e0226698.

  4. Gong J#, Chai L#, Xu, G, et al. 2018. The expression of natriuretic peptide receptors in developing zebrafish embryos. Gene Expression Patterns, 29, 65-71.

  5. Liu M, Pan J, Liu Z, Cheng Y, Gong J*, Wu X*. 2018. Effect of estradiol on vitellogenesis and oocyte development of female swimming crab, Portunus trituberculatus. Aquaculture, 486, 240-245.

  6. Lu Y, Liu M, Gong J*, Cheng Y, Wu X*. 2018. Effect of exogenous estrogen on the ovarian development and gene expression in the female swimming crab Portunus trituberculatus (Miers, 1876)(Decapoda: Brachyura: Portunidae). Journal of Crustacean Biology, 38(3), 367-373.

  7. Gong J, Wang X, Zhu CW, et al. 2017. Insm1a regulates motor neuron development in zebrafish, Frontiers in Molecular Neuroscience, 10, 274.

  8.  Gong J, Huang CC, Shu L, et al. 2016. The retinoid X receptor from mud crab: new insights into its roles in ovarian development and related signaling pathway. Scientific Reports, 6.

  9. Gong J, Ye HH, Xie YJ, et al. 2015. Ecdysteroid receptor in Scylla paramamosain: a possible role in promoting ovary development. Journal of Endocrinology, 224, 273287.

  10. Gong J, Ye HH, Yu K, et al. 2015. Evaluating the effects of temperature, salinity, starvation and autotomy on molting success, molting interval and expression of ecdysone receptor in early juvenile mud crabs, Scylla paramamosain. Journal of Experimental Marine Biology and Ecology, 464, 11-17.

  11. Gong J, Xie YJ, Yu K, et al. 2014. Characterization and expression analysis of chymotrypsin after bacterial challenge in the mud crab, Scylla paramamosain. Genetics and Molecular Biology, 37, 381-388.

  12. Shi, YW, Yuan, W, Wang, X, Gong, J, et al. 2016. Combretastatin A-4 efficiently inhibits angiogenesis and induces neuronal apoptosis in zebrafish. Scientific Reports, 6.