科研团队

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仿生材料与组织工程研究团队

日期:2020-05-16   点击数:11  

科研团队:仿生材料与组织工程研究团队

团队网站:https://www.x-mol.com/groups/BMTEers

一、团队研究方向:

南通大学仿生材料与组织工程研究团队的主要研究方向为:1. 临床生物医用材料与体外诊断试剂的研发;2. 功能复合材料;3. 仿生材料与组织工程;4. 药物可控缓释系统。团队围绕材料学、细胞与分子生物学、临床医学等多学科交叉,以仿生生物医用材料为工具重点探索支架与(干)细胞/组织相互作用机制、疾病诊断、药物可控释放系统、再生医学方面的基础和应用研究。

二、团队负责人简介

袁卉华博士, 副教授(校聘教授), 硕士生导师。江苏省六大人才高峰高层次人才。在生物材料、纳米技术、高分子复合材料等领域的学术刊物上发表SCI论文31篇(其中以第一作者或通讯作者发表SCI论文12篇,JCR一区论文6篇,二区论文2篇),获选SCI 期刊编辑的重点推荐(Editor’s Pick)及特色文章(Featured articles1篇(Biomed Mater 2014, 9(5):055001),目前SCI论文被引用达900余次,H-指数16,第一作者撰写英文专著的1个章节,获授权4项中国发明专利。是中国生物材料学会、中国生物医学工程学会、中国化学会会员以及国际组织工程与再生医学会员,也是Acta BiomaterMat Sci Eng C-MaterColloid Surface B以及J Cell Physiol 等国际学术期刊的受邀论文评审人。近年来,承担国家自然科学青年基金项目、江苏省自然科学青年基金项目、南通市科技计划项目等10项课题。

三、团队成员

教师

宣红云  博士、讲师(校聘副教授)

瞿建刚  博士、讲师

李碧云  博士、实验师

研究生    

熊峰(推免)

本科生

刘寅虎、杜茜、牛娜昕、姚波、魏硕、张卓君、刘旭、童心、高晓晓、黄泽鹏、卜嘉森

四、科研项目

2019-2021: 国家自然科学基金-青年项目:肌腱再生(袁卉华)

2018-2021: 江苏省自然科学基金-青年基金项目:肌腱再生(袁卉华)

2018-2020: 江苏省六大人才高峰高层次人才培养对象:肌腱再生(袁卉华)

2018-2020:江苏省产学研合作项目:纺织(瞿建刚)

2016-2018:江苏省高校自然科学研究面上项目:光催化(瞿建刚)

2019-2020:纺织面料技术教育部重点实验室开放基金项目:光热转化(瞿建刚)

2019-2021:南通市科技项目:气管软骨再生(李碧云)

2019-2021:南通市科技项目:神经再生(宣红云)

2019-2021:南通市科技项目:光热转化(瞿建刚)

2017-2019:南通市科技项目:肌腱再生(袁卉华)

2016-2018:南通市科技项目:光催化(瞿建刚)

五、主要论文及著作

1. Biyun Li#, Feng Xiong#, Bo Yao, Qian Du, Jun Cao, Jiangang Qu, Wei Feng*, Huihua Yuan*. Preparation and characterization of antibacterial dopamine-functionalized reduced graphene oxide/PLLA composite nanofibers. RSC Advances, 2020,10:18614 – 18623.

2. Hongyun Xuan, Xiaoxuan Tang, Yanxi Zhu, Jue Ling*, Yumin Yang*. Freestanding hyaluronic acid/silk-based self-healing coating towards tissue repair with antibacterial surface. ACS Applied Bio-materials, 2020,3(3):1628-1635.                                       

3. Hao Chen#, Biyun Li#, Bei Feng, Hao Wang, Huihua Yuan*, Zhiwei Xu*. Tetracycline hydrochloride loaded citric acid functionalized chitosan hydrogel for wound healing. RSC Advances, 2019, 9(34):19523-19530.                                                 

4. Hongyun Xuan, Yanxi Zhu, Jiaoyu Ren, Wei Dai, Liqin Ge*. Self-healing, antibacterial, and dual cross-linked multilayer films for microcapsule-based controllable drug release applications. Applied Surface Science, 2019, 476: 182-188.                                                                         

5. Hongyun Xuan, Yanxi Zhu, Jiaoyu Ren, Liqin Ge*. Intrinsic self-healing and biocompatibility of carbon nitride coatings via inhibiting or degrading ethylene for fruit preservation. Journal of materials science, 2019, 54: 9282-9290.

6. Jiangang Qu, Nanfei He, Shradha V. Patil, Yanan Wang, Debjyoti Banerjee, Wei Gao.Screen printing of graphene oxide patterns onto viscose nonwovens with tunable penetration depth and electrical conductivity. ACS Applied Materials Interfaces, 2019, 11:14944-14951.

7. Jiangang Qu, Nannan Li, Chunmei Wang, Jinxin He. Study of degradation products and degradation pathways of sulfonated azo dyes under ultraviolet irradiation.Textile Research Journal,

2019, 89(3):322-334.                             

8. Hao Chen#, Hao Wang#, Biyun Li#, Bei Feng, Xiaomin He, Wei Fu, Huihua Yuan*, Zhiwei Xu*. Enhanced chondrogenic differentiation of human mesenchymal stems cells on citric acid-modified chitosan hydrogel for tracheal cartilage regeneration applications. RSC Advances, 2018, 8(30): 16910-16917.                           

9. Hongyun Xuan, Wei Dai, Yanxi Zhu, Jiaoyu Ren, Jianhao Zhang, Liqin Ge*. Self-Healing, antibacterial and sensing nanoparticle coating and its excellent optical applications. Sensors and actuators B: Chemical, 2018, 257:1110-1117.                                               

10. Hongyun Xuan, Jiaoyu Ren, Xizhang Wang, Jianhao Zhang, Liqin Ge*. Flame-retardant, non-irritating and self-healing multilayer films with double-network structure. Composites Science and Technology, 2017, 145: 15-23.                                                                

11. Hongyun Xuan, Jiaoyu Ren, Jianhao Zhang, Liqin Ge*. Novel highly-flexible, acid-resistant and self-healing host-guest transparent multilayer films. Applied Surface Science, 2017, 411: 303-314.                                                                            

12. Huihua Yuan#, Jinbao Qin#, Jing Xie, Biyun Li, Zhepao Yu, Zhiyou Peng, Bingcheng Yi, Xiangxin Lou, Xinwu Lu*, Yanzhong Zhang*. Highly aligned core-shell structured nanofibers for promoting phenotypic expression of vSMCs for vascular regeneration. Nanoscale, 2016, 8(36): 16307-16322.                                       

13. Huihua Yuan, Yaxian Zhou, Ming-song Lee, Yanzhong Zhang*, Wanju Li*. A newly identified mechanism involved in regulation of human mesenchymal stem cells by fibrous substrate stiffness. Acta Biomaterialia, 2016, 42:247-257.                                                                  

14. Biyun Li#, Huihua Yuan#, Pengfei Yang, Bingcheng Yi, Yanzhong Zhang*. Fabrication of the composite nanofibers of NiO/γ-Al2O3 for potential application in photocatalysis. Ceramics International. 2016, 42(15): 17405-17409.                                                     

15. Biyun Li#, Shengqiang Pan#, Huihua Yuan, Yanzhong Zhang*. Optical and mechanical anisotropies of aligned electrospun nanofibers reinforced transparent PMMA nanocomposites. Composites Part A, Applied Science and Manufacturing, 2016, 90:380-389.                                                                     

16. Hongyun Xuan, Jiaoyu Ren, Yanxi Zhu, Xuefan Liu, Liqin Ge*. A green method to fabricate uniform porous responsive one-dimensional photonic crystals. Colloids and Surfaces A-physicochemical and Engineering Aspects, 2016, 507: 83-88.                                

17. Hongyun Xuan, Chong Yao, Xiaolong Hao, Cihui Liu, Jiaoyu Ren, Yanxi Zhu, Chunxiang Xu, Liqin Ge*. Fluorescence enhancement with one-dimensional photonic crystals/ nanoscaled ZnO composite thin films. Colloids and Surfaces A-physicochemical and Engineering Aspects, 2016, 6: 115247-115251.                  

18. Hongyun Xuan, Jiaoyu Ren, Yanxi Zhu, Bo Zhao, Liqin Ge*. Aptamer-functionalized P(NIPAM-AA) hydrogel fabricated one-dimensional photonic crystals (1DPCs) for colorimetric sensing. RSC Advances, 2016, 6: 36827-36833.

19. Huihua Yuan, Kai Li, Biyun Li, Xiangxin Lou, Qinghua Zhao*, Yanzhong Zhang*. Development of a novel elastic and macroporous chitosan hydrogel for wound healing application. Journal of Controlled Release, 2015, 213:e8-e152.                                              

20. Can Zhang#, Huihua Yuan#, Huanhuan Liu, Xiao Chen, Ping Lu, Ting Zhu, Long Yang, Zi Yin, Boon Chin Heng, Yanzhong Zhang*, Hongwei Ouyang*. Well-aligned chitosan-based ultrafine fibers committed teno-lineage differentiation of human induced pluripotent stem cells for Achilles tendon regeneration. Biomaterials, 2015, 53: 716–730.                                                               

21. Huihua Yuan, Qihui Zhou, Biyun Li, Min Bao, Xiangxin Lou, Yanzhong Zhang*. Direct printing of patterned three-dimensional ultrafine fibrous scaffolds by stable jet electrospinning for cellular ingrowth. Biofabrication, 2015, 7: 045004.                                                                          

22. Huihua Yuan, Biyun Li, Kai Liang, Xiangxin Lou, Yanzhong Zhang*. Regulating drug release from pH- and temperature-responsive electrospun CTS-g-PNIPAAm/poly(ethylene oxide) hydrogel nanofibers. Biomedical Materials, 2014, 9(5):055001. (Editor’s Pick, Featured articles)                                                         

23. Huihua Yuan, Hongbin Tu, Biyun Li, Qin Li, Yanzhong Zhang*. Aligned ultrafine chitosan fibers from stable jet electrospinning. Acta Polymerica Sinica, 2014, (1):131-140.

24. Jiangang Qu, Ruoyang Chen, Xia Dong, Jinxin He.Effect of NaCl concentrations on the photodecoloration of reactive azo-dyes and their cotton dyeings.Textile Research Journal, 2014, 84(20):2140-2148.

25. Biyun Li, Huihua Yuan, Yanzhong Zhang*. Transparent PMMA-based nanocomposite using electrospun graphene-incorporated PA-6 nanofibers as the reinforcement. Composites Science and Technology, 2013, 89:134-141.

26. Jiangang Qu, Nannan Li, Baojiang Liu, Jinxin He*. Preparation of BiVO4/bentonite catalysts and their photocatalytic properties under simulated solar irradiation.Materials Science in Semiconductor Processing, 2013, 16:99-105.                                                                     

27. Huihua Yuan, Shifang Zhao, Hongbin Tu, Biyun Li, Qin Li, Bei Feng, Hongju Peng, Yanzhong Zhang*. Stable jet electrospinning for easy fabrication of aligned ultrafine fibers. Journal of Materials Chemistry, 2012, 22(37):19634-19638.                                                                  

Book Chapter

1. Huihua Yuan#, Qihui Zhou#, Yanzhong Zhang*, 6. Improving fiber alignment during electrospinning, in Electrospun nanofibers, Editor: Mehdi Afshari, Woodhead Publishing, 2017. ISBN: 9780081009079.

六、联系方式以及其它信息

Email: yuanhh@ntu.edu.cn