仇嘉颖
姓名：仇嘉颖
职称：助理研究员、硕士生导师
部门：南通大学附属妇幼保健院
联系方式：qiujiaying@ntu.edu.cn
学历及学术经历：
2019年毕业于苏州大学，医学博士，江苏省双创博士，南通市“十四五”青年医学人才。主持国家自然科学基金青年项目1项；主持并完成南通市里科技局指令性项目1项，南通市卫健委面上A类项目1项；以第一作者或通讯作者发表SCI论文10余篇，影响因子累计大于50。
研究领域：神经损伤与修复/单基因遗传病的分子机制、诊断与药物研发
课题情况：
(1) 国家自然科学基金委员会, 面上项目, 52273131, 可透过血脑屏障且结构可控的聚合物载药体系的构建研究, 2023-01-01 至 2026-12-31, 53万元, 在研, 参与
(2) 国家自然科学基金委员会, 青年科学基金项目, 32200940, Scn5a互斥型剪接异构体介导失神经后肌类型特异性萎缩的机制研究, 2023-01-01 至 2025-12-31, 30万元, 在研, 主持
(3) 国家自然科学基金委员会, 面上项目, 82072160, IL-6/JAK/STAT3信号在失神经肌萎缩过程中的作用及机制研究, 2021-01-01 至 2024-12-31, 55万元, 在研, 参与
(4) 国家自然科学基金委员会, 面上项目, 81871554, HDAC4-MYOG抑制对失神经肌萎缩的保护作用及机制,2019-01-01 至 2020-12-31, 25万元, 结题, 参与
代表性文章：
(1) Jiaying Qiu; Ruobing Qu; Mengsi Lin; Jian Xu; Qingwen Zhu; Zhenyu Zhang; Junjie Sun; Position-dependent effects of hnRNP A1/A2 in SMN1/2 exon7 splicing, Biochimica et biophysica acta, 2022, 1865(8): 194875-194875
(2) Junjie Sun#; Jiaying Qiu#; Qiongxia Yang; Qianqian Ju; Ruobing Qu; Xu Wang; Liucheng Wu;Lingyan Xing ; Single-cell RNA sequencing reveals dysregulation of spinal cord cell types in a severe spinal muscular atrophy mouse model, PLOS Genetics, 2022, 18(9): e1010392-e1010392
(3) Jiaying Qiu; Liucheng Wu; Ruobing Qu; Tao Jiang; Jialin Bai; Lei Sheng; Pengchao Feng;Junjie Sun ; History of development of the life-saving drug “Nusinersen” in spinal muscular atrophy, Frontiers in Cellular Neuroscience, 2022, 16(942976)
(4) Jiaying Qiu; Liucheng Wu; Yan Chang; Hualin Sun; Junjie Sun ; Alternative splicing transitions associate with emerging atrophy phenotype during denervation-induced skeletal muscle atrophy, Journal of Cellular Physiology, 2021, 236(6): 4496-4514
(5) Mengsi Lin; Xinyi Hu; Shiyi Chang; Yan Chang; Wenjun Bian; Ruikun Hu; Jing Wang; Qingwen Zhu; Jiaying Qiu; Advances of Antisense Oligonucleotide Technology in the Treatment of Hereditary Neurodegenerative Diseases, Evidence-Based Complementary and Alternative Medicine, 2021, 2021(6678422): 1-9
(6)Yan Chang; Xiaofeng Lu; Jiaying Qiu；Compensatory expression regulation of highly homologous proteins HNRNPA1 and HNRNPA2, Turkish Journal of Biology, 2021, 45(2): 187
(7) Jiaying Qiu; Xiaoming Yang; Lingbin Wang; Qiuyu Zhang; Wenjing Ma; Ziwei Huang; Yuhua Bao; Lou Zhong; Hualin Sun; Fei Ding, Isoquercitrin promotes peripheral nerve regeneration through inhibiting oxidative stress following sciatic crush injury in mice, Annals of Translational Medicine, 2019, 7(22): 680
(8) Jiaying Qiu; Jianwei Zhu; Ru Zhang; Wenpeng Liang; Wenjing Ma; Qiuyu Zhang; Ziwei Huang; Fei Ding; Hualin Sun, miR-125b-5p targeting TRAF6 relieves skeletal muscle atrophy induced by fasting or denervation, Annals of Translational Medicine, 2019, 7(18): 456